The dose of a drug required to produce a specified effect in 50% of the population is_____________?

Related Mcqs:

1. The ratio of the median lethal dose of the median effective dose is the_____________?

   A. Morbidity index
   B. Moratality index
   C. Anesthetic ratio
   D. Therapeutic index

2. Drug not requiring dose adjustment in renal disease is___________?

   A. Aminoglycoside
   B. Vancomycin
   C. Calcium channel blocker
   D. Metronidazole

3. Drug binds to activate the receptor is same fashion, which directly or indirectly brings effect, is_____________?

   A. Inverse agonist
   B. Antagonist
   C. Agonist
   D. Partial agonist

4. The following adverse effect of penicillin is dose related___________?

   A. Skin rash
   B. Intersititial Nephritis
   C. Drug fever
   D. Encephalopathy

5. Loading dose depends on_____________?

   A. Volume of distribution
   B. Clearance
   C. Rate of administration
   D. Half life

6. During administration of NSAIDs in children, the most important of dose administration is______________?

   A. Weight of the child
   B. Age of child
   C. Nature of the drug
   D. Chronicity of pain

7. When a drug creates an effect that is unpredictable and unique it is termed as____________?

   A. Side effect
   B. Toxicity effect
   C. Idiosyncratic effect
   D. Drug on Drug effect

8. In cirrhoses patients, dose reduction is needed for all the following drugs except_____________?

   A. Lorazepam
   B. Theophylline
   C. Paracetamol
   D. Metronidazole

9. A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?

   A. Rifampicin
   B. Isoniazide
   C. Pyrazamide
   D. Ethambutol

10. A paralyzing dose of succinylcholine initially elicits______________?

    A. CNS stimulation
    B. Muscle fasciculation
    C. CNS depression
    D. Decreased salivation