A. Volume of distribution
B. Clearance
C. Rate of administration
D. Half life
Related Mcqs:
- The ratio of the median lethal dose of the median effective dose is the_____________?
A. Morbidity index
B. Moratality index
C. Anesthetic ratio
D. Therapeutic index - The dose of a drug required to produce a specified effect in 50% of the population is_____________?
A. Ld50
B. Td50
C. Md50
D. Ed50 - During administration of NSAIDs in children, the most important of dose administration is______________?
A. Weight of the child
B. Age of child
C. Nature of the drug
D. Chronicity of pain - Which of the following is not an action of epinephrine when administered intravenously in a high dose ?
A. Increased liver glycogenolysis
B. Causes broachiolar constriction
C. Evokes extrasystoles in the heart
D. Produces restlessness and anxiety - The following adverse effect of penicillin is dose related___________?
A. Skin rash
B. Intersititial Nephritis
C. Drug fever
D. Encephalopathy - Drug not requiring dose adjustment in renal disease is___________?
A. Aminoglycoside
B. Vancomycin
C. Calcium channel blocker
D. Metronidazole - Which factor of the following contributes to short duration of anesthetic action of single dose thiopental_____________?
A. Rapid biotransformation
B. Rapid accumulation in body fat
C. High lipid solubility
D. Ability to enter and leave brain tissue every rapidly - In cirrhoses patients, dose reduction is needed for all the following drugs except_____________?
A. Lorazepam
B. Theophylline
C. Paracetamol
D. Metronidazole - A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?
A. Rifampicin
B. Isoniazide
C. Pyrazamide
D. Ethambutol - A paralyzing dose of succinylcholine initially elicits______________?
A. CNS stimulation
B. Muscle fasciculation
C. CNS depression
D. Decreased salivation
