Loading dose depends on_____________?

Related Mcqs:

1. The ratio of the median lethal dose of the median effective dose is the_____________?

   A. Morbidity index
   B. Moratality index
   C. Anesthetic ratio
   D. Therapeutic index

2. The dose of a drug required to produce a specified effect in 50% of the population is_____________?

   A. Ld50
   B. Td50
   C. Md50
   D. Ed50

3. During administration of NSAIDs in children, the most important of dose administration is______________?

   A. Weight of the child
   B. Age of child
   C. Nature of the drug
   D. Chronicity of pain

4. Which of the following is not an action of epinephrine when administered intravenously in a high dose ?

   A. Increased liver glycogenolysis
   B. Causes broachiolar constriction
   C. Evokes extrasystoles in the heart
   D. Produces restlessness and anxiety

5. The following adverse effect of penicillin is dose related___________?

   A. Skin rash
   B. Intersititial Nephritis
   C. Drug fever
   D. Encephalopathy

6. Drug not requiring dose adjustment in renal disease is___________?

   A. Aminoglycoside
   B. Vancomycin
   C. Calcium channel blocker
   D. Metronidazole

7. Which factor of the following contributes to short duration of anesthetic action of single dose thiopental_____________?

   A. Rapid biotransformation
   B. Rapid accumulation in body fat
   C. High lipid solubility
   D. Ability to enter and leave brain tissue every rapidly

8. In cirrhoses patients, dose reduction is needed for all the following drugs except_____________?

   A. Lorazepam
   B. Theophylline
   C. Paracetamol
   D. Metronidazole

9. A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?

   A. Rifampicin
   B. Isoniazide
   C. Pyrazamide
   D. Ethambutol

10. A paralyzing dose of succinylcholine initially elicits______________?

    A. CNS stimulation
    B. Muscle fasciculation
    C. CNS depression
    D. Decreased salivation