Hepatic first pass metabolism is important in____________?

Related Mcqs:

1. Drugs exhibiting first pass metabolism are all EXCEPT one______________?

   A. Morphine
   B. Nitroglycerine
   C. Propranolol
   D. Salicylates

2. A young pregnant woman presents with fulminant hepatic failure. The most likely aetiological agent is_____________?

   A. Hepatitis B virus
   B. Hepatitis C virus
   C. Hepatitis E virus
   D. Hepatitis A virus

3. Function of hepatic kupffer cells is____________?

   A. Formation of sinusoids
   B. Vitamin-A storage
   C. Increases blood perfusion
   D. Phagocytosis

4. The phase I reactions of drug metabolism include The following except_____________?

   A. Hydolysis
   B. Reduction
   C. Oxidation
   D. Conjugation

5. All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?

   A. Tetracycline
   B. Cimetidine
   C. Rifampicin
   D. Phenobarbitone

6. Following drug which undergo most of its metabolism presystemically______________?

   A. Salbutamol
   B. Verapamil
   C. Propranolol
   D. Paracetamol

7. 1st past metabolism effect can be observed with which route______________?

   A. Oral
   B. Inhalation
   C. Rectal
   D. Parental

8. Which of the following drugs when used for prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin like drugs?

   A. Phenobarbital.
   B. Meprobamate
   C. Chlordiazepoxide
   D. Triazolam
   E. Zolpidum

   Submitted by: Dr.Tassawer-e-Meran

9. Bone metabolism is controlled by ____________?

   A. Vit – D & Calcium
   B. Parathormone
   C. Calcitonin
   D. All of the above

10. The main pathways of metabolism in brain are______________?

    A. Glycolysis and citric acid cycle
    B. Glycogenolysis and Gluconeogenesis
    C. Embden-Meyerhof Pathway and H.M.P shunt
    D. Glycogenolysis and Citric and cycle