Following drug which undergo most of its metabolism presystemically______________?

Related Mcqs:

1. The phase I reactions of drug metabolism include The following except_____________?

   A. Hydolysis
   B. Reduction
   C. Oxidation
   D. Conjugation

2. All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?

   A. Tetracycline
   B. Cimetidine
   C. Rifampicin
   D. Phenobarbitone

3. HMP shunt is of great importance in cellular metabolism because its produces_____________?

   A. ATP
   B. ADP
   C. Acetyl CoA
   D. NADPH

4. Which of the following drugs when used for prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin like drugs?

   A. Phenobarbital.
   B. Meprobamate
   C. Chlordiazepoxide
   D. Triazolam
   E. Zolpidum

   Submitted by: Dr.Tassawer-e-Meran

5. Hepatic first pass metabolism is important in____________?

   A. Drugs given IM
   B. Drugs taken orally
   C. Drugs given IV
   D. None of the above

6. Drugs exhibiting first pass metabolism are all EXCEPT one______________?

   A. Morphine
   B. Nitroglycerine
   C. Propranolol
   D. Salicylates

7. Which of the following hormones exerts the least effect on calcium metabolism of bone tissue ?

   A. Anderogen
   B. Estrogen
   C. Nor epinephrine
   D. Thyroid hormone

8. 1st past metabolism effect can be observed with which route______________?

   A. Oral
   B. Inhalation
   C. Rectal
   D. Parental

9. The cells which do not undergo mitotic divisions___________?

   A. Smooth muscle cells
   B. Endotheilial cells
   C. Bone marrow cells
   D. Neurons

10. Ketone bodies are by products of metabolism of_____________?

    A. Carbohydrate
    B. Protein
    C. Fat
    D. All of the above