1st past metabolism effect can be observed with which route______________?

Related Mcqs:

1. Which of the following hormones exerts the least effect on calcium metabolism of bone tissue ?

   A. Anderogen
   B. Estrogen
   C. Nor epinephrine
   D. Thyroid hormone

2. The phase I reactions of drug metabolism include The following except_____________?

   A. Hydolysis
   B. Reduction
   C. Oxidation
   D. Conjugation

3. Hepatic first pass metabolism is important in____________?

   A. Drugs given IM
   B. Drugs taken orally
   C. Drugs given IV
   D. None of the above

4. All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?

   A. Tetracycline
   B. Cimetidine
   C. Rifampicin
   D. Phenobarbitone

5. Drugs exhibiting first pass metabolism are all EXCEPT one______________?

   A. Morphine
   B. Nitroglycerine
   C. Propranolol
   D. Salicylates

6. Following drug which undergo most of its metabolism presystemically______________?

   A. Salbutamol
   B. Verapamil
   C. Propranolol
   D. Paracetamol

7. Which of the following drugs when used for prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin like drugs?

   A. Phenobarbital.
   B. Meprobamate
   C. Chlordiazepoxide
   D. Triazolam
   E. Zolpidum

   Submitted by: Dr.Tassawer-e-Meran

8. Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to lack of_____________?

   A. Parahydroxy phenyl pyruvate Hydroxylase
   B. Tyrosine transaminase
   C. Homogentisate oxidase
   D. Tyrosine oxidase

9. Albinism is a genetic disease that results in incomplete metabolism of______________?

   A. Histidine
   B. Cystine
   C. Tyrosine
   D. Alanine

10. Ketone bodies are by products of metabolism of_____________?

    A. Carbohydrate
    B. Protein
    C. Fat
    D. All of the above