Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?

Related Mcqs:

1. In TCA cycle or tricarboxylic acid cycle, which is first formed________________?

   A. Isocitrate
   B. Citrate
   C. Succinate
   D. Fumarate

2. In TCA cycle substrate level phosphorylation occurs at____________?

   A. Succinate dehydrogenase
   B. Malonate reduction
   C. Thiokinase
   D. None of the above

3. In TCA cycle, citrate is converted in to after losing a molecule of H2O_____________?

   A. Isocitrate
   B. Cisaconitate
   C. Oxalocetate
   D. Glutarate

4. The main enzyme responsible for activation of xenobiotics in (detoxification)____________?

   A. Cytochrome P-450
   B. Glutathione S-transferase
   C. NADPH cytochrome P-450 reductase
   D. Glucuronyl transferase

5. The following chemical mediator is a product of arachidonic acid metabolite by cyclo oxygenase pathway____________?

   A. LxA4
   B. LxB4
   C. 5-HETE
   D. PGH2

6. Which one is not converted to an active metabolite ?

   A. Quinapril
   B. Fosinopril
   C. Benzopril
   D. Lisinopril

7. In TCA, substrate level phospherylation takes place in______________?

   A. Alpha ketoglutrate to succinyl CoA
   B. Succinyl CoA to Succinate
   C. Succinate to fumarate
   D. Oxalocetate to citrate

8. Detoxification of drugs is controlled by_____________?

   A. Cytochrome
   B. Cytochrome P450
   C. Cytochrome C
   D. Cytochrome A

9. Detoxification or protective synthesis occurs by____________?

   A. Oxidation
   B. Reduction
   C. Conjugation
   D. Any of the above

10. Major source of ammonia in the kidney is___________?

    A. Urea Aspartate
    B. Aspartate
    C. Glutamine
    D. Glutamate