At PH 7 the binding of 2,3 DPG to hemoglobin occurs at which site ?

Related Mcqs:

1. What effect does hyperventilation have on the oxygen binding affinity of hemoglobin ?

   A. P50 and oxygen affinity decrease
   B. P 50 and oxygen affinity increase
   C. P 50 decreases and the oxygen affinity increases
   D. P50 increase and the oxygen affinity decreases

2. The binding site for complement on the IgG molecule is in the________________?

   A. VL domian
   B. CL domian
   C. CH1 domian
   D. CH2 domian

3. Which of the following is correct about breakdown of hemoglobin (Hb)_____________?

   A. Hb→Heme→bilirubin→Urobilinogen
   B. Heme→Hb→Biliverdin→Urobilinogen
   C. Hb→Heme→Bilverdin→Uro bilinogen
   D. Hb→Heme→bilirubin→Urobilinogen→Biliverdin

4. Which of the following is not a part of hemoglobin molecule___________?

   A. Pyrrole rings
   B. Vinyl groups
   C. Histidine
   D. Ferric ions

5. When horse serum is injected intravenoulsy in to a rabbit and again in to the skin two or three weeks later, what is the necrotizing reaction that occurs as the site of the second injection________________?

   A. Atopy
   B. Anaphylaxis
   C. Arthus phenomenon
   D. Serum sickness

6. A small Ca+2 binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca+2 concentration is known as______________?

   A. Cycline
   B. Calmodulin
   C. Collagen
   D. Kinesin

7. The hemoglobin % of a normal newborn is______________?

   A. 8
   B. 12
   C. 10
   D. 30

8. Embryonic hemoglobin is composed of________________?

   A. Gamma and beta
   B. Epsilon and gamma
   C. Alpha and beta
   D. Gamma and alpha

9. Hemoglobin has______________?

   A. Four polypeptide chains, 2α, 1β,1Υ chain
   B. Four heme molecules and four polypeptide chains
   C. Four heme molecules, 2α and 2β chains
   D. One heme and one globin molecule

10. A patient reports with dyspnoea on slight exertion. He also has multiple petechial spots and spontaneous hemorrhage. His RBC count is less than one lakh/mm3 His hematocrit and hemoglobin is low. Most probable diagnosis is______________?

    A. Pernicious anemia
    B. Thalassemia
    C. Aplastic anemia
    D. Sprue