A. It is the proportion (fraction) of unchanged drug that reaches the systemic circulation
B. Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration
C. Low oral biovailability always and necessarily mean poor absorption
D. Biovailability can be determined from plasma concentration or urinary excretion data
0
Combination of ampicillin and gentamicin is an example of_____________?
0
Which drugs had high first pass effect_____________?
A. Indifference
B. Synergy
C. Antagonism
D. Bacterial symbiosis
0
Neuro adaptation to drug is same as______________?
A. Amiodarone
B. Phenytoin
C. Verapamil
D. Disorpyamide
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Idiosyncracy is known as to have_____________?
A. Physical dependence
B. Psychological dependence
C. Addiction
D. Habituation
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Zero order kinetics is seen with_______________?
A. Genetic component
B. Psychological component
C. Psysiological component
D. Nutritional component
0
Drugs showing zero order kinetics of elimination_____________?
A. Phenytoin
B. Phenabarbtion
C. Erythromycin
D. Digoxin
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Therapeutic index is____________?
A. Are more common than first order kinetics
B. Decrease in concentration exponentially with time
C. Have a half – life independent of dose
D. Show a plot of drug concentration versus time that is linear
0
Allergic reactions depends on all except____________?
A. LD 100/Ed100
B. ED 100/LD 100
C. LD 50/ED500
D. ED50/LD50
0
When allergic manifestations occur pursuant to use of antimicrobial agents, what of the following is seen____________?
A. previous exposure to the drug
B. Dosage of the drug received
C. Pharmacological action of the drug
D. Antigen antibody reaction
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