Select the drug that undergoes extensive first-pass metabolism in the liver:

Related Mcqs:

1. Glomerular filtration of a drug is affected by its:____________?

   A. Lipid solubility
   B. Plasma protein binding
   C. Degree of ionization
   D. Rate of tubular secretion

   Submitted by: Dr.Tassawer-e-Meran

2. If a drug is eliminated by first order kinetics:

   A. A constant amount of the drug will be eliminated per unit time
   B. Its clearance value will remain constant
   C. Its elimination half life will increase with dose
   D. It will be completely eliminated from the body in
   2 × half life period

   Submitted by: Dr.Tassawer-e-Meran

3. Which of the following is an idiosyncratic adverse drug reaction:

   A. Muscle dystonia caused by triflupromazine
   B. Insomnia after taking pentobarbitone
   C. Precipitation of asthma by morphine
   D. Gum hyperplasia caused by phenytoin

   Submitted by: Dr.Tassawer-e-Meran

4. The nature of propellant is determined by ____________?

   A. R-F method
   B. Gas Chromatography
   C. UV
   D. None

   Submitted by: Dr.Tassawer-e-Meran

5. Which one of the following techniques can be used for the detection in a liquid chromatograph?

   A. Ultraviolet absorbance or refractive index measurement.
   B. Increase in temperature
   C. Ionization in flame
   D. Thermal conductivity

   Submitted by: Dr.Tassawer-e-Meran

6. Which one of the following arrangements for the sequence of the main components of a Uv/visible spectrophotometer is Correct?

   A. Light source  Detector  Sample cell  Monochromator  Readout
   B. Light source  Sample cell  Detector  Monochromator  Readout
   C. Light source  Readout  Sample cell  Detector  Monochromator
   D. None of these

   Submitted by: Dr.Tassawer-e-Meran

7. The energy associated with infra red is enough to make__________?

   A. electronic transitions
   B. vibrational and rotational transitions
   C. a full separation of the electron in the outer shell
   D. X-ray fluorescence
   E. an electron move from an inner orbital

   Submitted by: Dr.Tassawer-e-Meran

8. Narrow line spectra are emitted by___________?

   A. hot solids
   B. excited polyatomic molecules
   C. molecules in the ground molecular state
   D. excited atoms

   Submitted by: Dr.Tassawer-e-Meran

9. Microsomal enzyme induction can be a cause of___________?

   A. Tolerance
   B. Physical dependence
   C. Psychological dependence
   D. Idiosyncrasy

   Submitted by: Dr.Tassawer-e-Meran

10. Use of an emetic to remove the ingested poison is contraindicated in following poisonings except that by:

    A. Strychnine
    B. Caustic soda
    C. Ferrous sulfate
    D. Kerosene

    Submitted by: Dr.Tassawer-e-Meran