The phase I reactions of drug metabolism include The following except_____________?

Related Mcqs:

1. All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?

   A. Tetracycline
   B. Cimetidine
   C. Rifampicin
   D. Phenobarbitone

2. Following drug which undergo most of its metabolism presystemically______________?

   A. Salbutamol
   B. Verapamil
   C. Propranolol
   D. Paracetamol

3. The major factors predisposing to thrombogenesis include all of the following except_____________?

   A. Endothelial injury
   B. Hyper coagulability of blood
   C. Altered blood flow
   D. Pattern of blood flow

4. Essential granulation tissue constituents include all except_____________?

   A. Fibroblast
   B. Macrophages
   C. Polymorphs
   D. Budding blood vessels

5. Features characteristic of leukoplakia include all except_____________?

   A. Hyperkeratosis
   B. Plasma cell infiltration within the dermal papilae
   C. Clinically, a paint like patch
   D. A moist shiny lesion

6. Which of the following drugs when used for prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin like drugs?

   A. Phenobarbital.
   B. Meprobamate
   C. Chlordiazepoxide
   D. Triazolam
   E. Zolpidum

   Submitted by: Dr.Tassawer-e-Meran

7. Hepatic first pass metabolism is important in____________?

   A. Drugs given IM
   B. Drugs taken orally
   C. Drugs given IV
   D. None of the above

8. Drugs exhibiting first pass metabolism are all EXCEPT one______________?

   A. Morphine
   B. Nitroglycerine
   C. Propranolol
   D. Salicylates

9. Which of the following hormones exerts the least effect on calcium metabolism of bone tissue ?

   A. Anderogen
   B. Estrogen
   C. Nor epinephrine
   D. Thyroid hormone

10. 1st past metabolism effect can be observed with which route______________?

    A. Oral
    B. Inhalation
    C. Rectal
    D. Parental